Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4153
Gene Symbol: MBL2
MBL2
CUI: C3714514
Disease: Infection
Infection
0.400 AlteredExpression LHGDN Mannose-binding lectin and susceptibility to infection in Chinese patients with systemic lupus erythematosus. 17552055

2007

Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C3714514
Disease: Infection
Infection
0.400 AlteredExpression LHGDN Characterization of soluble FAS, FAS ligand and tumour necrosis factor-alpha in patients with chronic HCV infection. 16087126

2005

Entrez Id: 1401
Gene Symbol: CRP
CRP
CUI: C3714514
Disease: Infection
Infection
0.350 AlteredExpression LHGDN Significant association between Helicobacter pylori infection and serum C-reactive protein. 18695743

2008

Entrez Id: 3458
Gene Symbol: IFNG
IFNG
CUI: C3714514
Disease: Infection
Infection
0.100 AlteredExpression LHGDN Gastric mucosal cytokine responses in Helicobacter pylori-infected patients with gastritis and peptic ulcers. Association with inflammatory parameters and bacteria load. 12738388

2003

Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C3714514
Disease: Infection
Infection
0.100 AlteredExpression LHGDN Transforming growth factor-beta expression induced by rhinovirus infection in respiratory epithelial cells. 17151785

2006

Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C3714514
Disease: Infection
Infection
0.100 AlteredExpression LHGDN Interleukin-1beta expression in human gastric carcinoma with Epstein-Barr virus infection. 12050395

2002

Entrez Id: 7099
Gene Symbol: TLR4
TLR4
CUI: C3714514
Disease: Infection
Infection
0.100 AlteredExpression LHGDN Monocyte toll-like receptor 4 expression and LPS-induced cytokine production increase during gestational aging. 15879290

2005

Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C3714514
Disease: Infection
Infection
0.100 AlteredExpression LHGDN Dominant expression of interleukin-10 and transforming growth factor-beta genes in activated T-cells of chronic active Epstein-Barr virus infection. 15368517

2004

Entrez Id: 7099
Gene Symbol: TLR4
TLR4
CUI: C3714514
Disease: Infection
Infection
0.100 AlteredExpression LHGDN Toll-like receptors 3 and 4 are expressed by human bone marrow-derived mesenchymal stem cells and can inhibit their T-cell modulatory activity by impairing Notch signaling. 17962701

2008

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C3714514
Disease: Infection
Infection
0.100 AlteredExpression LHGDN 5-aza-2'-deoxycytidine upregulates caspase-9 expression cooperating with p53-induced apoptosis in human lung cancer cells. 15273730

2004

Entrez Id: 7099
Gene Symbol: TLR4
TLR4
CUI: C3714514
Disease: Infection
Infection
0.100 AlteredExpression LHGDN Ehrlichia chaffeensis downregulates surface Toll-like receptors 2/4, CD14 and transcription factors PU.1 and inhibits lipopolysaccharide activation of NF-kappa B, ERK 1/2 and p38 MAPK in host monocytes. 14706103

2004

Entrez Id: 7099
Gene Symbol: TLR4
TLR4
CUI: C3714514
Disease: Infection
Infection
0.100 AlteredExpression LHGDN Superantigen recognition by HLA class II on monocytes up-regulates toll-like receptor 4 and enhances proinflammatory responses to endotoxin. 15644417

2005

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C3714514
Disease: Infection
Infection
0.100 AlteredExpression LHGDN Helicobacter pylori infection generated gastric cancer through p53-Rb tumor-suppressor system mutation and telomerase reactivation. 12508351

2003

Entrez Id: 3458
Gene Symbol: IFNG
IFNG
CUI: C3714514
Disease: Infection
Infection
0.100 AlteredExpression LHGDN Interferon-gamma receptors in HIV-1 infection. 18620489

2008

Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C3714514
Disease: Infection
Infection
0.100 AlteredExpression LHGDN Hepatitis C virus core protein upregulates transforming growth factor-beta 1 transcription. 14635011

2004

Entrez Id: 3586
Gene Symbol: IL10
IL10
CUI: C3714514
Disease: Infection
Infection
0.100 AlteredExpression LHGDN Gastric mucosal cytokine responses in Helicobacter pylori-infected patients with gastritis and peptic ulcers. Association with inflammatory parameters and bacteria load. 12738388

2003

Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C3714514
Disease: Infection
Infection
0.100 AlteredExpression LHGDN R5 human immunodeficiency virus type 1 infection of fetal thymic organ culture induces cytokine and CCR5 expression. 15596839

2005

Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C3714514
Disease: Infection
Infection
0.100 AlteredExpression LHGDN IL-10 and TGF-beta redundantly protect against severe liver injury and mortality during acute schistosomiasis. 18981143

2008

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C3714514
Disease: Infection
Infection
0.100 AlteredExpression LHGDN p53 gene mutations are rare in human papillomavirus-associated colon cancer. 14534749

2004

Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C3714514
Disease: Infection
Infection
0.100 AlteredExpression LHGDN Exaggerated IL-8 and IL-6 responses to TNF-alpha by parainfluenza virus type 4-infected NCI-H292 cells. 15273081

2004

Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C3714514
Disease: Infection
Infection
0.100 AlteredExpression LHGDN Differential regulation of Moraxella catarrhalis-induced interleukin-8 response by protein kinase C isoforms. 18184679

2008

Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C3714514
Disease: Infection
Infection
0.100 AlteredExpression LHGDN Regulation of CXCL-8 (interleukin-8) induction by double-stranded RNA signaling pathways during hepatitis C virus infection. 17035306

2007

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C3714514
Disease: Infection
Infection
0.100 AlteredExpression LHGDN Human papillomavirus infection in oral verrucous carcinoma: genotyping analysis and inverse correlation with p53 expression. 18580072

2008

Entrez Id: 1234
Gene Symbol: CCR5
CCR5
CUI: C3714514
Disease: Infection
Infection
0.100 AlteredExpression LHGDN CCR5 receptor expression is down-regulated in HIV type 2 infection: implication for viral control and protection. 15242539

2004

Entrez Id: 3458
Gene Symbol: IFNG
IFNG
CUI: C3714514
Disease: Infection
Infection
0.100 AlteredExpression LHGDN Inhibition of IFN-gamma-induced STAT1 tyrosine phosphorylation by human CMV is mediated by SHP2. 18832710

2008